DEVELOPMENT OF ORGANOID BASED MODEL TO STUDY IMMUNE-NEURAL INTERACTIONS IN HUMAN CNS DISEASES
Joanna Kocot, Sahar H. Pradhan, Dragan Maric, Peter Kosa et autres
ABSTRACT Modeling neural-immune interactions in neurodegenerative and immune-mediated central nervous system (CNS) diseases requires human 3D models that capture cellular diversity and long-term tissue maturation. Here, we present an enhanced human induced pluripotent stem cell (hiPSC)-derived cerebral organoid (CO) platform optimized to …
us (code pays fourni par la source)