In Silico Decoding of Nonsteroidal Mineralocorticoid Receptor Antagonist Binding: Implications for Drug Design
Felipe Pérez-Gordillo, Laureano E. Carpio, Diego Álvarez de la Rosa, Mercedes Martín‐Martinez
The mineralocorticoid receptor (MR), a member of the steroid hormone nuclear receptor subfamily, mediates the effects of aldosterone and glucocorticoids. Initially characterized in epithelial tissues as a key regulator of blood pressure, MR was later found to be widely expressed across multiple …
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Journal of Chemical Information and Modeling