Impact of timing of aggressive joint PK/PD target attainment of continuous infusion piperacillin-tazobactam on early clinical response of febrile neutropenia to antimicrobial treatment: Insights from a prospective, monocentric, observational study in paediatric hematopoietic stem cell recipients
Milo Gatti, Davide Leardini, Caterina Campoli, Francesco Venturelli et autres
Objective To evaluate the impact of timing of aggressive joint pharmacokinetic/pharmacodynamic (PK/PD) target attainment of continuous infusion (CI) piperacillin-tazobactam on early clinical response in pediatric hematopoietic stem cell (HSCT) recipients with febrile neutropenia (FN). Methods This prospective, monocentric, observational study included pediatric …
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International Journal of Antimicrobial Agents