Hyodeoxycholic acid suppresses hepatic steatosis in a PPARα-dependent manner via distinct GLP-1- and iNKT cell-mediated pathways
Eunyoung Lee, Ryo Hatano, Mariko Takami, Masanori Fujimoto et autres
Hepatosteatosis is a common metabolic disorder. Bile acids influence hepatosteatosis, immune function, and incretin secretion. However, whether bile acids mediate hepatosteatosis through these immune or endocrine pathways remain unknown. Here, we identify supplementation with hyodeoxycholic acid (HDCA) in high-fat diet-fed mice increases …
jp, gb, tw (code pays fourni par la source)
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Cell Reports