Multi-omics integrated with machine learning identifies LPS-related genes potentially associated with iron metabolism-Immune axis imbalance in PCOS: a bioinformatics-based exploration of mechanisms and diagnostic markers
Yang Li, Chunmei Bai, Xumin Zhang, Haixia Song et autres
Abstract Chronic low-grade inflammation induced by bacterial lipopolysaccharide has been implicated in the pathogenesis of polycystic ovary syndrome; however, the genetic mechanisms linking lipopolysaccharide signaling to immune and metabolic dysregulation remain insufficiently elucidated. In the present study, transcriptomic datasets and single-cell sequencing …
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