Accès ouvert
2026
preprint
OpenAlex
Lindsay A. Osso, Helena J. Barr, Michael E. Stockton, Maureen Wentling et autres
Microglia are the predominant immune cells in multiple sclerosis (MS) demyelinating lesions, where they phagocytose myelin, but whether they destroy myelin or merely scavenge its debris is unknown. Here, we explore whether pathogenic autoantibodies found in MS may induce the phagocytic destruction …
us, gb, fr
(code pays fourni par la source)
2026
article
OpenAlex
Hoi Kiu Wong, Samantha Ho, Qian Yu, Katherine S. Given et autres
The identification of autoantibodies against aquaporin-4 (AQP4) and myelin oligodendrocyte glycoprotein (MOG) has been essential in distinguishing neuromyelitis optica spectrum disorder (NMOSD) and MOG antibody-associated disease (MOGAD) from classical multiple sclerosis (MS), with important implications for treatment. However, for several patients within …
de, at, us, se
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Roaya S. Alqurashi, Audrey Yee, Taylor J. Malone, Sumaiah Alrubiaan et autres
Epilepsy is a complex neurological condition characterized by repeated spontaneous seizures and can be induced by initiating seizures known as status epilepticus (SE). Elaborating the critical molecular mechanisms following SE are central to understanding the establishment of chronic seizures. Here, we identify …
us, sa
(code pays fourni par la source)