Lipid-conjugated Ru( iii ) complexes as inhibitors of pathological peptide aggregation in neurodegenerative disorders
Claudia Riccardi, Ettore Napolitano, Chiara Platella, Andrea Conte et autres
5 μM for both compounds). More detailed studies on their interaction with AD peptides revealed their capacity to be coordinated by histidine residues in the N-terminal region. Biological investigations on human neuroblastoma-derived cells indicated no relevant cytotoxicity at concentrations comparable to those …
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RSC Medicinal Chemistry