Characterization of persistent HPV-specific activated T cells in head and neck squamous cell carcinoma
Hiromasa Ishihara, Hirofumi Shibata, Daisuke Muraoka, Ayako Demachi‐Okamura et autres
Background Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV + OPSCC) generally has favorable outcomes yet remains prone to late recurrence. Durable control likely depends on persistent tumor-specific CD8+ T cells, but their persistence and function in metastasis are poorly understood.Methods We integrated …
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OncoImmunology