Furanocarboxamide Derivative Against Congenital Toxoplasmosis: Synthesis, Bioactivity, ADME Profile and in silico Insights
Júlia O. Carvalho, Ana Paula C. Procópio, Marcos Paulo Oliveira Almeida, Beatriz A. Vasconcelos et autres
Congenital toxoplasmosis remains a significant therapeutic challenge within the spectrum of Toxoplasma gondii infections is estimated about 190,000 cases per year, with a considerable infection rate worldwide (ca. 29%). This study describes the synthesis and pharmacological evaluation of compound 1, a furanocarboxamide …