Condensates of the chromatin regulator ANKRD11 restrict hypertranscribed genes to safeguard development
Tao Zhang, Xiufeng Li, Wei Zhou, LI Zhao-lu et autres
Genes that define cell identity are often highly transcribed, but how their activity is regulated to prevent pathological dysregulation remains elusive. Using a two-tiered genetic screen, we identify a network of genes regulating hypertranscribed loci, which is notably enriched for genes mutated …
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Cell