PCET‐Inspired Nanoparticles Enable Paired Proton‐Electron Delivery to Restore Mitochondrial Electron Transport and Regenerate Bone During Aging
Kelei Wang, Xiayu Hu, Changfen Bi, Yimai Zhuang et autres
Mitochondrial electron transport chain (ETC) dysfunction drives the accumulation of damaged mitochondria and bioenergetic insufficiency, contributing to cellular senescence and impaired tissue repair in aging. However, reconstituting ETC-associated mitochondrial bioenergetics in situ to overcome this energy restriction remains challenging. In this study, …
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