Immune organization defines adaptive immune competence and clinical outcome in breast cancer
Esther Sanfeliu, Elia Seguí, Anabel Martínez-Romero, Víctor Albarrán et autres
Summary Tumor-infiltrating lymphocytes (TILs) are widely used to assess antitumor immunity in breast cancer but may not reflect the functional competence of adaptive immune responses. We show that immune organization, reflected by tertiary lymphoid structures (TLS) and coordinated humoral and cellular immune …
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