Accès ouvert
2026
article
OpenAlex
Julian U. G. Wagner, Hamza Gulshan, Ibrahim Sultan, Salli Antila et autres
Aging is a major risk factor for cardiovascular disease, but the role of the cardiac lymphatic vasculature in this process remains poorly understood. Here we show that aging reduces cardiac lymphatic vessel density in humans and mice and induces structural remodeling characterized …
de, fi, at
(code pays fourni par la source)
2026
article
OpenAlex
Olaniyi Olarewaju, Martin Bentler, J Breuer, Fatih Alioglu et autres
Receptor engagement plays a key role in the cellular uptake, intracellular trafficking, and overall transduction efficiency of adeno-associated virus (AAV) vectors. Although heparan sulfate proteoglycan (HSPG) and α5ß1 integrin-binding motifs of the AAV serotype 2 (AAV2) capsid were mapped, it has remained …
de, at
(code pays fourni par la source)
2026
article
OpenAlex
Irem Duman, Christoph Kugler, Verena Schwingenschlögl-Maisetschläger, Haider Sami et autres
We present an innovative bioanalytical hybrid platform designed for the preclinical evaluation of cellular characteristics. The system combines a three-dimensional (3D) cell culture grown on an artificial extracellular matrix with a chromatography-inspired array configuration. Sponges, made from the structural protein silk fibroin, …
at
(code pays fourni par la source)