Zhendong Xin

Preparation of monoclonal antibodies against Echinococcus multilocularis CIP2A and development of blocking and sandwich ELISAs

Xinyi Zhou, Lijuan Zheng, Yong Fu, Ting Zhang et autres

cn (code pays fourni par la source)

The establishment of a universal blocking ELISA for echinococcosis using immunoglobulin against a new conserved linear B-cell epitope

Guoyan Zhou, Lijuan Zheng, Zhendong Xin, Jun He et autres

ABSTRACT Echinococcosis is a neglected tropical disease that poses a severe threat to global public health and socioeconomic development. Given its alarming global spread, there is an urgent need to develop accurate diagnostic methods to support targeted and personalized treatment. Echinococcus multilocularis …

cn, us (code pays fourni par la source)

Cyclo-C stabilizes PEX13 to inhibit porcine epidemic diarrhea virus replication by blocking pexophagy-mediated disruption of antiviral innate immunity

Jin-xiu Lou, Zhiwei Guo, Kang Chen, Yuanmingyue Tian et autres

ABSTRACT The persistent threat of porcine epidemic diarrhea virus (PEDV) to the global swine industry is compounded by high neonatal piglet mortality and the absence of effective antiviral therapies. Host-directed strategies that reinforce immunity offer a promising avenue to counter viral immune …

cn (code pays fourni par la source)

A novel activation-related gene P158 is essential for evagination and early development of Echinococcus multilocularis protoscoleces

Zhendong Xin, Zhen Wang, Yong Fu, Chenye Jin et autres

BACKGROUND: Alveolar echinococcosis is a lethal zoonotic parasitic disease caused by Echinococcus multilocularis. The activation and subsequent evagination of protoscoleces (PSCs) in the host digestive tract are critical steps for establishing infection in definitive hosts, yet the underlying molecular mechanisms remain poorly …

cn, jp (code pays fourni par la source)