Razan Abbara

Confidence metrics used in the AlphaFold Database multimers

Razan Abbara

Protein complexes play essential roles in many cellular processes, and the arrangement of their subunits is often critical to their function. AlphaFold Database (AFDB) multimer predictions provide valuable structural insights into these assemblies, but interpreting their confidence scores requires care. Developed and …

gb (code pays fourni par la source)

AlphaFold Database expands to proteome-scale quaternary structures

Jennifer R. Fleming, Yewon Han, Maxim Tsenkov, Niccolo Venanzi et autres

kr, gb, us, ru (code pays fourni par la source)

Protein domains: structure, classification, and evolution

Razan Abbara, Antonina Andreeva, Alex Bateman, Jennifer R. Fleming et autres

This tutorial provides a practical introduction to protein domains, explaining how to recognise, classify, and interpret them, and how to apply this knowledge across a wide range of life science research.

gb (code pays fourni par la source)

AlphaFold Database expands to proteome-scale quaternary structures

Yewon Han, Maxim I. Tsenkov, Niccolo A. E. Venanzi, Sooyoung Cha et autres

Abstract Protein function is governed by molecular interactions, yet structural coverage of these interactions remains sparse. The AlphaFold Protein Structure Database (AFDB) transformed access to accurate monomeric protein structures at scale. Here, we expand the AFDB to quaternary structures by predicting 31M …

kr, gb, us (code pays fourni par la source)