The Role of the Bone Marrow Microenvironment in the Pathogenesis of Acute Myeloid Leukemia
Michele Gottardi, Federico De Marchi, Giulia Ciotti, Marco Basso et autres
Acute myeloid leukemia (AML) develops within a bone marrow environment that influences leukemic stem cell behavior, residual disease, and response to therapy. This review examines evidence that the marrow microenvironment is not only a site of leukemic growth, but can actively shape …
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