Kyle LaPenna

Convergent roles of GDF-15 in mechanotransduction, vascular disorganization, and immune suppression in melanoma

Yu-Chi Chen, Vishnu Sravan Bollu, Sina Kheirabadi, Kyle LaPenna et autres

Melanoma, particularly in its advanced forms, remains one of the most lethal skin cancers, with limited effective treatments for both common cutaneous subtypes and rarer variants such as acral melanoma. The effects of the extracellular matrix (ECM) and other cancer-cell extrinsic processes …

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A case report of fulminant primary purulent pericarditis due to Streptococcus pyogenes presenting with cardiac tamponade in a seemingly immunocompetent adult

Kyle LaPenna, Jonathon Mitchell, John Mancini, Khanh Pham et autres

Abstract Background Primary purulent pericarditis due to Streptococcus pyogenes is exceedingly rare in adults, with fewer than 10 cases reported in the literature to date. Most reported cases have occurred in the setting of an immunocompromised state, thoracic procedures, or identifiable infectious …

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An Investigation of Elevated Serum Copper Levels Following Bariatric Surgery

Katherine McKeon, Michael Cook, John Baker, Kyle LaPenna et autres

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