The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of Pf Ark1 and Hemozoin Formation
Kathryn J. Wicht, John G. Woodland, Larnelle F. Garnie, Henrico Langeveld et autres
High Resolution Image Download MS PowerPoint Slide The high burden of malaria and growing resistance to frontline antimalarials demand new drug target combinations with reduced propensities for conferring parasite resistance. An attractive approach for circumventing antimalarial drug resistance is target repurposing, in …
Afrique du Sud, ca, Éthiopie, us, de, fr, gb, ch, cz (code pays fourni par la source)
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ACS Chemical Biology