Accès ouvert
2026
article
OpenAlex
Hao Cheng Shen, Marie Hudson, Susanna Proudman, Jenny Walker et autres
Abstract Background Autoantibodies against NOR-90 are rare and have been associated with systemic sclerosis (SSc). This study seeks to identify the characteristics of SSc participants with anti-NOR-90 autoantibodies. Methods An international (Canada, Australia, USA, Mexico) cohort of 2143 SSc participants was included. …
ca, au, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand et autres
OBJECTIVE: The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. METHODS: Participants enrolled in the Canadian Scleroderma Research Group cohort who self-identified to a single ethnicity group were included. …
ca
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Cheng Shen, Marie Hudson, Susanna Proudman, Jenny Walker et autres
Introduction Autoantibodies against NOR-90 are rare and have been associated with systemic sclerosis (SSc). This study seeks to identify the characteristics of SSc participants with anti-NOR-90 autoantibodies. Material and Methods An international (Canada, Australia, USA, Mexico) cohort of 2143 SSc participants were …
ca, au, us
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Danick Goulet, Camille Guertin, Maggie Larché, Marie Hudson et autres
Introduction Non-White individuals generally present with distinct and more severe systemic sclerosis (SSc) phenotypes compared to White individuals. We further characterized and compared demographic, clinical, and serological characteristics, as well as mortality and disease progression, of Canadian SSc patients according to race/ethnicity …
ca
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Tatiana Nevskaya, Maggie Larché, Murray Baron, Sabrina Hoa et autres
Introduction The prevalence of sicca and/or objective signs of Sjogren’s syndrome (SjS) in systemic sclerosis (SSc) patients varies from 1/3 and higher.1 2 The differences between patients with SSc+SjS vs SSc and no SjS with respect to manifestations, functional status and quality …
ca
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Charmaine van Eeden, Janet Elizabeth Pope, Udo Douwe J. Mulder, Desiree Redmond et autres
Introduction Severe fatigue frequently affects patients with rheumatic diseases. We have previously shown that mitochondrial dysregulation, elevated inflammatory markers (e.g. Galectin-9), and reduced lung function are associated with severe fatigue in systemic sclerosis (SSc) patients. The oxygen-transport-cascade, which encompasses the heart/lungs, hemoglobin/oxygen …
ca, nl, au
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Chloé Jessen, Claudie Berger, Maggie Larché, May Choi et autres
Introduction Pulmonary arterial hypertension (PAH) is a leading cause of mortality in systemic sclerosis (SSc). PAH is typically considered as a late complication, but some evidence suggests it may occur earlier. We aimed to assess the incidence, risk factors, clinical characteristics, and …
fr, ca
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Chloé Jessen, Mireille Schnitzer, Maggie Larché, May Choi et autres
Introduction Pulmonary arterial hypertension (PAH) is a major cause of death in systemic sclerosis (SSc) and, despite significant advances, still responds poorly to vasodilator therapy. Histopathological and experimental data suggest an immune-mediated vascular mechanism, raising the hypothesis that immunosuppressive therapy could prevent …
fr, ca
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Sabrina Hoa, Marcelo Veiga Da Silva, Mathieu Rousseau, Catherine Faucher et autres
Introduction Interstitial lung disease (ILD) is the leading cause of mortality in systemic sclerosis (SSc). Half present with mild disease, of whom 25% progress over two years. Our aim was to explore the role of quantitative chest high-resolution computed tomography (HRCT) in …
ca
(code pays fourni par la source)
Accès ouvert
2026
conference-abstract
OpenAlex
Sabrina Hoa, Danick Goulet, Yumeko Kawano, Susanna Proudman et autres
Introduction Interstitial lung disease (ILD) is a leading cause of mortality in systemic sclerosis (SSc). Half present with mild disease, of whom 25% progress over two years. Our aim was to explore demographic, clinical, and serological predictors of progression in mild SSc-ILD. …
ca, us, au
(code pays fourni par la source)