Deciphering melanoma brain metastases: Role of cellular plasticity and metastatic origin
Shanice J. Heidenreich, Jessica Faber, Markus Lorke, Dayana Herrera-Rios et autres
The treatment of brain metastases in malignant melanoma remains one of the major clinical challenges despite immuno-oncological and targeted therapies. Here, we revealed that successful colonization of the brain by melanoma cells is primarily determined by two complementary factors: (i) intrinsic phenotypic …
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Biomaterials Advances