Profil bibliographique

Mengyao Lu

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

2Publications signalées
0Citations signalées
2Affiliations récentes

Les institutions déclarées

University of PittsburghPurdue University West Lafayette

Les domaines associés

Ubiquitin and proteasome pathwaysSingle-cell and spatial transcriptomicsinterferon and immune responsesHistone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors

Les publications récentes

2026 preprint OpenAlex

A Time-Resolved Single-Cell Atlas Reveals Infection-Status, Age-, and Sex-Dependent Immune Responses Drive Viral Disease Severity

Lujia Chen, Anchen Qiu, JooYoung Kim, N Abu Hussein et autres

Abstract The majority of mortality during viral infections occurs in older males; however, underlying mechanisms by which age and sex shape antiviral immunity and pathological inflammatory responses remain incompletely understood. Here, we performed time-resolved single-cell RNA sequencing across 16 conditions spanning age, …

us, cn (code pays fourni par la source)

0 citations bioRxiv (Cold Spring Harbor Laboratory)
Accès ouvert 2026 preprint OpenAlex

Identification, optimization, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for Ubiquitin C-terminal Hydrolase L3

Nagabhushana C. Beeralingappa, Mengyao Lu, Rishi Patel, Nipuni Pannala et autres

Abstract The deubiquitinating enzyme, ubiquitin C-terminal hydrolase L3 (UCHL3), has been implicated as a potential therapeutic target for cancer with a role in regulating the DNA damage response pathways. While the target has been studied using genetic methods there is a lack …

us (code pays fourni par la source)

0 citations bioRxiv (Cold Spring Harbor Laboratory)
Notice OpenAlex

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