Genetic variation in antidiabetic drug targets: associations with Parkinson’s disease risk and age at onset
Katalin Vincze, Agnieszka Szwajda, Alexander Ploner, Robert Karlsson et autres
To investigate whether antidiabetic drugs have a biological basis to be repurposed in PD prevention, we applied a drug target Mendelian randomization framework to assess associations between genetic variation in antidiabetic drug targets and PD risk or age at onset (AAO). Instrumental …
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npj Parkinson s Disease