First-in-human PET imaging of 68 Ga-FC516, a novel ACP3-targeted radiotracer for prostate cancer.
Kongzhen Hu, Ruitao Yang, Lu Wang, Huiyi Wei et autres
5128 Background: Prostatic acid phosphatase (ACP3) is overexpressed in more than 85% of prostate cancers, and largely absent in normal tissues, resulting in over 100-fold tumor-to-background specificity. ACP3 represents a differentiated imaging biomarker that may complement prostate-specific membrane antigen (PSMA), particularly in …
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Journal of Clinical Oncology