Accès ouvert
2026
article
OpenAlex
Wei Zhang, Xianji Wei, 陈民铀, L ei Zhang et autres
Osteopontin (OPN), encoded by the SPP1/Spp1 gene, is increasingly recognized as an extracellular matrix-associated immunoregulatory molecule in the central nervous system (CNS). In CNS-related contexts, OPN does not act as a uniformly protective or detrimental factor. Instead, its effects depend on the …
cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang et autres
Multi-organ degenerative diseases are ageassociated or chronic disorders marked by progressive tissue deterioration, impaired repair and functional decline, with representative conditions including sarcopenia, osteoporosis, osteoarthritis, neurodegenerative or ischemia-associated neurological disorders, heart failure, chronic kidney disease and diabetes-associated tissue dysfunction.Their frequent coexistence in …
cn, gb
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Xianji Wei, Yuxiang Du, Xiaohua Liu, L ei Zhang
Basonuclin 2 (BNC2) is a highly conserved cysteine-histidine (C2H2)-type zinc-finger nuclear regulatory protein characterized by three pairs of zinc-finger domains, a putative nuclear localization signal, a serine-rich region, broad tissue distribution, and remarkable transcript diversity generated through alternative promoter usage, alternative splicing, …
cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Chengyan Guo, Xianji Wei, wenjing Li, Guanyi Wang et autres
Skeletal muscle is an important locomotor and metabolic organ in the human body and plays a central role in maintaining physical activity, energy homeostasis, and structural support. Although skeletal muscle possesses a certain regenerative potential, under pathological conditions such as aging, severe …
cn, gb, mo
(code pays fourni par la source)