Shiva Mostafavi

Relationship betweenintegrated myocardial flow reserve (iMFR) andobstructive coronary artery disease and majoradversecardiac events:Findingsfrom the multi-center REFINE PET registry

Waseem Hijazi, Shiva Mostafavi, Aakash Shanbhag, Robert JH. Miller et autres

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A Two-Stage Multimodal Contrastive Framework for PET-Based Prediction of Obstructive Coronary Artery Disease

Shiva Mostafavi, Aakash Shanbhag, Giselle Ramirez, Mark Lemley et autres

Abstract Background Positron emission tomography (PET) myocardial perfusion imaging (MPI) provides complementary information on perfusion, myocardial blood flow and ventricular function. While these markers are often considered collectively during interpretation, their quantitative integration with imaging and clinical data into a unified predictive …

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Beyond BMI: an interpretable integrated body composition index from low-dose chest CT for all-cause mortality risk stratification: a multicentre study

Jirong Yi, Krishna K. Patel, Robert J.H Miller, Anna M Marcinkiewicz et autres

Summary Background Body composition is recognized as a major determinant of health outcomes, but its multidimensional nature makes clinical adoption challenging. We sought to develop and validate a body composition index (BCI) for all-cause mortality risk assessment, integrating variables of six body …

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Patient-specific timing acquisition for coronary CT angiography: A retrospective patient validation study

Sabee Molloi, Shiva Mostafavi, Alireza Shojazadeh, Kyrillos Grace et autres

Purpose: To retrospectively validate a patient-specific post-trigger delay technique for coronary CT angiography (CCTA) and compare it with the conventional fixed-delay approach using true peak arterial enhancement as the reference standard. Methods: Thirty-seven patients (mean age 63 ± 9 years; 35% male) …

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Single-cell sequencing unveils a profibrotic macrophage and infiltrating monocyte niche in the bronchoalveolar lavage of patients with chronic obstructive pulmonary disease

Firoozeh V. Gerayeli, Chen Xi Yang, Carolyn Wang, Xuan Li et autres

RATIONALE: Chronic obstructive pulmonary disease (COPD) is characterized by global immune dysregulation. The most abundant immune cells in the distal airways and alveolar compartments are macrophages and lymphocytes. These cells have been poorly characterized in human airways due to their plasticity and …

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