Enrico Verrina

How we do it: functional magnetic resonance urography in congenital anomalies of the kidney and urinary tract

Lorenzo Anfigeno, Luca Basso, Giulia Gnocchi, Luca Barbieri et autres

Congenital anomalies of the kidney and urinary tract (CAKUT) are among the leading causes of chronic kidney disease in children. Early and accurate evaluation is essential to preserve nephron mass and guide appropriate management. Ultrasound represents the first-line imaging modality and acts …

it, us (code pays fourni par la source)

The landscape of serum autoantibodies in lupus nephritis

Maurizio Bruschi, Federico Alberici, Gabriella Luisa Moroni, Augusto Vaglio et autres

it, ca, ch (code pays fourni par la source)

SGLT2i, anti-endothelin A and double endothelin and angiotensin inhibitors: a new future for chronic kidney disease in children

Edoardo La Porta, Elisa Russo, Decimo Silvio Chiarenza, Enrico Verrina et autres

Chronic kidney disease (CKD) in childhood, although uncommon, has profound lifelong consequences. Because disease onset occurs early, even modest slowing of CKD progression may translate into decades free from dialysis, transplantation, and premature death. Progressive proteinuria is a central driver of nephron …

it (code pays fourni par la source)

Steroid-Resistant Idiopathic Nephrotic Syndrome Reveals a Distinct Maladaptive Molecular State

Sonia Spinelli, Sofia Gaudiano, Andrea Garbarino, Francesca Lugani et autres

Introduction: Idiopathic nephrotic syndrome (iNS) is clinically classified by treatment response; however, the molecular basis of multidrug resistance remains poorly defined. We hypothesized that multidrug-resistant disease represents a distinct biological state rather than a more severe form of active disease. Methods: Serum …

it (code pays fourni par la source)

IgM Hyposialylation Modulates Podocyte Vulnerability in Patients With Idiopathic Nephrotic Syndrome

Sonia Spinelli, Sofia Gaudiano, Andrea Garbarino, Francesca Lugani et autres

Introduction: Altered Ig glycosylation has been implicated in antibody-mediated podocytopathies; however, the functional relevance of IgM sialylation remains poorly defined. Previous evidence suggests that circulating cationic or hyposialylated IgM may contribute to podocyte vulnerability in idiopathic nephrotic syndrome (iNS). Methods: Serum IgM …

it (code pays fourni par la source)