Myocardial Fibrosis in Cardiovascular Disease: An Integrative Biomarker–Imaging Framework Linking Molecular Mechanisms to Structural Phenotypes
Mateusz Świątko, Jakub Baran, Aleksandra Czernicka, Łukasz Dudek et autres
Background: Myocardial fibrosis (MF) is a dynamic remodeling process characterized by excessive extracellular matrix (ECM) deposition, fibroblast activation, and dysregulated matrix turnover. Although initially reparative, persistent fibrotic remodeling promotes myocardial stiffening, electrical instability, and progressive cardiac dysfunction across diverse cardiovascular diseases. Circulating …
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