Pharmacokinetic drug-drug interaction between the COVID-19 3CL protease inhibitor GST-HG171 and itraconazole in healthy subjects
X.C. Li, Bing Li, Meng Wang, Yi-Xiang Wang et autres
ABSTRACT GST-HG171 (also known as atilotrelvir) is a novel, orally administered 3CL protease inhibitor approved in China for treating mild-to-moderate COVID-19. In this study, we assessed the drug-drug interaction between GST-HG171 (boosted with ritonavir) and itraconazole (a strong CYP3A inhibitor) in healthy …
cn, kr (code pays fourni par la source)
0 citations
Antimicrobial Agents and Chemotherapy