CYP2D6 phenotype and post-surgical pain control with hydrocodone and oxycodone
Christelle Lteif, Rachel A. Myers, Erica N. Elwood, Elizabeth Harris et autres
Background Hydrocodone and oxycodone are widely used for acute postoperative pain and are metabolized by CYP2D6 to more potent agonists. The clinical impact of CYP2D6 metabolizer status on hydrocodone and oxycodone analgesic response remains uncertain. This secondary analysis of A Depression and …
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