Tryptophan pathway metabotypes associate with disease activity and immune-metabolic dysfunction in inflammatory bowel disease
Danielle M M Harris, Arno R. Bourgonje, Peder Rustoen Braadland, Cathy McShane et autres
Abstract Background Tryptophan (Trp) metabolism is a central immunometabolic axis in inflammatory bowel disease (IBD) and has been linked to inflammatory activity and immune regulation. While individual Trp metabolites have been associated with disease severity and treatment response, systems-level frameworks to define …
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medRxiv