Molecular Dynamics Simulations of 4 GALC Variants Causing Krabbe Disease
Piet Ankermann, Silja I. Jenne, Jannes Talarek, Lukas Heger et autres
gene of patients with Krabbe disease. To investigate the effects of these mutations on protein structure, structural models of human GALC were built. These models served as the basis for a series of all-atom molecular dynamics (MD) simulations to analyze the structural …
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Computational and Structural Biotechnology Journal