Structure–Activity Relationship of Cyanine Dyes in Relation to the Hepatic Uptake and Excretion
Nataliia S. Berehova, Emily L. J. de Bock, Maarten P. van Meerbeek, Chanel M. Naar et autres
BACKGROUND: Indocyanine green (ICG) is a clinically approved fluorescent dye that is used for lesion identification during hepatobiliary surgery. However, the chemical structure of ICG seems to be suboptimal for this excretion-based diagnostic readout. In this study the effect of systematic structural …
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