Manuel Rodríguez‐Perálvarez

EP425 - ECE_2237 - Molecular and functional characterization of aminoacyl-tRNA synthetases in hepatocellular carcinoma

María Serrano-Jiménez, Natalia Hermán-Sánchez, Belén Gracia-Herencia, Manuel Rodríguez‐Perálvarez et autres

Abstract Introduction Nutrient availability and amino acid homeostasis are central regulators of metabolic and endocrine function in the liver. Alterations in amino acid sensing and utilization contribute to metabolic reprogramming in metabolic dysfunction–associated steatotic liver disease (MASLD), a major driver of liver-related …

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EP909 - ECE_2236 - RNA-exosome dysregulation: core and PAXT complexes as novel mediators of MASLD-HCC oncogenesis

Maria Isabel Pozo-Relano, Victor J. Fernandez-Ramirez, Samanta Lozano de la Haba, Manuel Rodríguez‐Perálvarez et autres

Abstract Metabolic-associated steatotic liver disease (MASLD) has emerged as the primary chronic liver dysfunction worldwide, frequently culminating in the development of hepatocellular carcinoma (HCC). Emerging evidence underscores the critical importance of RNA metabolism and surveillance in liver pathophysiology, where the RNA-Exosome complex …

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Complete Immunosuppression Withdrawal After Liver Transplantation: An International Multicenter Study

Roberta Angelico, Bruno Sensi, Giuseppe Tisone, Sandy Feng et autres

BACKGROUND & AIMS: Immunosuppression withdrawal after liver transplantation is feasible in selected individuals but the risk of chronic graft damage is unknown. We aimed to describe the clinical characteristics and long-term outcomes of patients with successful immunosuppression withdrawal after liver transplantation. METHODS: …

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SAT-268 Reassessing the utility of the Ferritin-IgG score in predicting complete biochemical response in patients with autoimmune hepatitis from the ColHai registry: is it truly useful?

Alvaro Diaz-Gonzalez, Bastian Engel, Manuel Hernández-Guerra, Indhira Perez Medrano et autres

OS-091 Long-term outcomes of patients with complete immunosuppression withdrawal after liver transplantation: a multicentre, worldwide study

Manuel Rodríguez‐Perálvarez, Bruno Sensi, Giuseppe Tisone, Sandy Feng et autres

SAT-256-YI Biochemical changes and clinical outcomes after obeticholic acid withdrawal in patients with primary biliary cholangitis

Beatriz Carrillo Cubero, Alba Carmona Frías, Paloma Elma Alañón-Martínez, J.L. Montero et autres

FRI-558 Excluding ascites from the GEMA-Na score does not impact outcome predictions in liver transplant candidates

Manuel Rodríguez‐Perálvarez, Antonio M. Gómez-Orellana, Avik Majumdar, Geoff McCaughan et autres

TOP-278 Factors associated with the development of primary biliary cholangitis in individuals with antimitochondrial antibodies: a spanish multicenter study

Alvaro Diaz-Gonzalez, Helena Hernandéz Evole, Lucía Jiménez, Manuel Rodríguez‐Perálvarez et autres

REACT Score, a Novel Scoring System, Improves the Prediction of Non‐Elective Readmissions in Patients With Decompensated Cirrhosis

Yolanda Sánchez‐Torrijos, Ana Torres‐Domínguez, Isabel Carmona, Luis Ibañez-Samaniego et autres

BACKGROUND AND AIM: One third of patients with cirrhosis experience an early readmission, and predicting such an event is challenging. We developed and validated a scoring system to predict non-elective readmissions in patients with cirrhosis. METHODS: An observational and multicenter retrospective study …

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