A model for Crohn’s disease post-ileal resection fibrosis development using human ileal enteroids and myofibroblasts
Jun Hwan Yoo, Yoon Jeong Choi, Iryna V. Pinchuk, Don W. Powell et autres
Background Fibrosis and inflammation frequently emerge soon after ileal resection for strictures in Crohn’s disease (CD). Objective This study examined the profibrotic and proinflammatory effects of conditioned media from TNF and IFN-γ (T+I)-exposed healthy and inactive CD ileal enteroids (CDiE) on subepithelial …
us, kr (code pays fourni par la source)
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Frontiers in Physiology