Role of the cross-regulation between Wnt pathway activation and androgen receptor signaling in prostate cancer treatment resistance
Nicolás Anselmino, Pablo Sanchis, Juan Antonio Bizzotto, Estefanía Labanca et autres
Prostate cancer (PCa) is a biologically heterogeneous disease that frequently progresses to castration-resistant prostate cancer (CRPC), a challenging clinical stage. The underlying mechanisms driving CRPC progression and resistance to androgen receptor (AR) signaling inhibition (ARSI) remain incompletely understood. Emerging evidence implicates the …
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Cell Death and Differentiation