Accès ouvert
2026
article
OpenAlex
Wanliang Sun, Shuo Zhou, Zhong Liu, Song Yang et autres
BACKGROUND: Hepatocellular carcinoma (HCC) is not only a widespread malignant tumor but also the third leading cause of cancer-related deaths. It has been reported that the expression level of H2AFY in HCC cells and tissues is relatively high and it contributes to …
cn
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Accès ouvert
2026
article
OpenAlex
Sihua Liu, Xiao You, Dongdong Wang, X M Wang et autres
Cholangiocarcinoma (CCA) is a highly aggressive malignancy. 3-Hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2), a mitochondrial enzyme involved in ketogenesis, has been linked to tumor progression, but its role in CCA remains unclear. HMGCS2 expression in CCA tissues was analyzed using TCGA data and immunoblotting …
cn, gb
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Wanliang Sun, Yifei Wang, Xuxu Qiao, Shuo Zhou et autres
Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive biological behavior and limited therapeutic responsiveness. Identifying genetically and biologically interpretable biomarkers remains critical for improving molecular stratification of this malignancy. Here, we performed an integrative analysis combining bulk transcriptomics, genomic alteration profiling, immune-response …
cn
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