Bone adhesive with temporally-synchronized degradation for enhanced osteointegration
Jun-ting Gu, Zhi-ting Li, Yuzhu Wang, Dong-xiao Hao et autres
Bone adhesives have emerged as promising alternatives for complex fracture fixation. However, discrepancies between material degradation rates and the physiological timeline of bone healing remain a critical limitation. Here, a polyurethane-based adhesive (TNC) was developed, synthesized from trimeric hexamethylene diisocyanate, nano-hydroxyapatite, and …
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