Sina Schalbetter

Probiotic treatment rescues behavioral deficits and gut microbial abnormalities induced by preconceptional stress in mothers and offspring

Monica Iachizzi, Natalia Zajac, José Luis Ruiz, Tanja Güller et autres

• Preconception stress alters maternal microbiota and induces anxiety-like behavior. • Probiotic supplementation normalizes stress-related microbial and behavioral changes. • Maternal microbial alterations are transmitted to offspring gut communities. • Probiotic exposure rescues offspring anxiety and cognitive deficits in a sex-dependent manner. …

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GABAergic Gbx1 neurons of the superficial dorsal horn are critical elements of a spinal circuit for stress-induced analgesia

Karen Haenraets, Robert P. Ganley, Francesca Pietrafesa, Donald Iain MacDonald et autres

Acute stress is a powerful inducer of endogenous analgesia. Several brainstem and midbrain areas have been identified that are activated during stress and send descending axons to suppress spinal nociception. The spinal effector circuits and neurons have, however, remained largely elusive. Here, …

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Astroglial disinhibition of cortical circuits disrupts cognition via kynurenic acid

Tina Notter, Viktor Beilmann, Johanna Furrer, Sina Schalbetter et autres

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