ERBB2 copy number alterations and protein expression in bladder cancer treated by cystectomy
John C. Cheville, Burak Tekin, Jacob J. Orme, Rafael E. Jimenez et autres
The introduction of antibody-drug-conjugates (ADC) that target HER2 has renewed interest in ERBB2 alterations in bladder cancer. Little is known about the frequency of ERBB2 copy number alterations in primary bladder cancer subtypes and regional nodal metastases, and the effect of amplification …
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