Mitochondrial transplantation for osteoarthritis: from molecular mechanisms to clinical translation
Ying Liu, Yang Liu, Nan Zhang, Haizhuan An et autres
Osteoarthritis (OA) is the most prevalent chronic degenerative joint disorder worldwide, characterized by progressive cartilage degradation, subchondral bone remodeling, synovial inflammation, and impaired mobility. Growing evidence has established mitochondrial dysfunction-including impaired oxidative phosphorylation (OXPHOS), excessive reactive oxygen species (ROS) generation, disrupted mitochondrial …
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5 citations
Frontiers in Immunology