Profil bibliographique

Nahian Khan

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

3Publications signalées
3Citations signalées
1Affiliations récentes

Les institutions déclarées

Pfizer (United States)

Les domaines associés

Carbohydrate Chemistry and SynthesisZeolite Catalysis and SynthesisChemical Synthesis and AnalysisSynthetic Organic Chemistry MethodsInorganic and Organometallic Chemistry

Les publications récentes

2026 article OpenAlex

Early Development of Ibuzatrelvir: Navigating Polymorph and Crystallization Challenges in a Protecting Group-Free Direct Amidation and Amidation-Dehydration Sequence

María González‐Esguevillas, Aaron F. Baldwin, Pablo J. Cabrera, Yanfei Guan et autres

Abstract Ibuzatrelvir is an orally bioavailable, next-generation clinical candidate developed for the treatment of COVID-19 infections. It was identified during the pandemic, prior to the approval of PAXLOVID, and displays a more favorable pharmacokinetic profile than nirmatrelvir. Consequently, the initial development of …

us (code pays fourni par la source)

0 citations Organic Process Research & Development
2026 article OpenAlex

Synthesis of Danuglipron: Development of a Scalable Alkylation and Chemoselective Hydrolysis Sequence

Ijaz Ahmed, Russell F. Algera, Aaron F. Baldwin, Andrew M. Derrick et autres

Abstract The target compound danuglipron belongs to a family of glucagon-like peptide-1 receptor agonist (GLP-1RA) candidates identified in the Pfizer laboratories for the treatment of type 2 diabetes mellitus and obesity. This article describes a development approach providing a data-centric, holistic methodology …

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0 citations Organic Process Research & Development
2026 article OpenAlex

Potassium tert -Butoxide: Solubility, Solution Structure, and Reactivity

Russell F. Algera, Nahian Khan, Philipp C. Roosen

Fundamental properties including solubility and structure–reactivity correlations of potassium tert -butoxide (KO t Bu) are described in this manuscript. A combination of donor solvent titration, diffusion NMR, and DFT studies established that KO t Bu exists in one of three solution structures: …

us (code pays fourni par la source)

3 citations The Journal of Organic Chemistry
Notice OpenAlex

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