Ilenia Rolli

Abstract 4897: Characterization of the intratumoral microbiota in non endemic EBV associated nasopharyngeal carcinoma

Deborah Lenoci, Federico Rossignoli, Armando G Licata, Marta Lucchetta et autres

Abstract Epstein-Barr virus (EBV) related nasopharyngeal carcinoma (NPC) is an epithelial malignancy arising from the nasopharyngeal mucosal lining. A high incidence of EBV related NPC is recorded in endemic areas (EA), East and Southeast Asia. Microbiota resides the upper respiratory tract including …

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Fragmenting the future with FLARE: a comprehensive fragmentomics pipeline based on long-read nanopore sequencing

Marica Ficorilli, Marta Lucchetta, Deborah Lenoci, Ilenia Rolli et autres

Purpose: Cell-free DNA (cfDNA) fragmentation patterns carry biological information beyond fragment length, revealing nuclease activity, chromatin organization, and tissue of origin. Fragmentomics has emerged as a powerful approach to improve circulating tumor DNA (ctDNA) detection, particularly at low tumor fractions. However, most …

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Characterization of the Intratumoral Microbiota in Non-Endemic EBV-Related Nasopharyngeal Carcinoma

Deborah Lenoci, Federico Rossignoli, Armando G Licata, Marta Lucchetta et autres

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