Preclinical characterization of immune responses induced by a candidate gonococcal native outer membrane vesicle vaccine
Ilaria Onofrio, Sthefany Pagliari, Ayah Francis, Molly E Quinn et autres
ABSTRACT Neisseria gonorrhoeae poses significant public health challenges due to multidrug-resistant gonorrhea and severe reproductive health complications of untreated infection. No vaccine is licensed to prevent gonorrhea. However, the meningococcal outer membrane vesicle (OMV)-containing vaccine, 4CMenB, provides moderate cross-protection against gonorrhea. We …
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