CSF microtubule-associated protein 1 light chain 3A and 3B levels are associated with tau pathology and Alzheimer’s disease risk through amyloid deposition and microglial signaling
Hai-Hua Guo, Dan Su, Bo Song, Zhi Geng et autres
BACKGROUND: Autophagy has recently attracted increasing attention for its critical involvement in Alzheimer’s Disease (AD) pathogenesis. However, the role of microtubule-associated protein 1 light chain 3 A (LC3A) and B (LC3B), key autophagic-associated proteins in cognitive decline, AD risk, and underlying pathology …
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