Mice with postsurgical pain exhibit age-dependent spinal microglial activation and inhibitory synapse loss.
Yi-Xiang Wang, Yu Shen, Shi-Hao Wang, Ping Sung Liao et autres
Persistent postsurgical pain is a major clinical concern, especially in the aging population, who represent a growing proportion of surgical patients. Although age is a known pain risk factor, the mechanisms driving age-related vulnerability to chronic postoperative pain remain poorly understood. This …
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