Guillermo J. Pons-Estel

Herpes zóster en pacientes con enfermedades reumáticas inflamatorias crónicas autoinmunes: un llamado a la acción

Francisco Nacinovich, Gustavo Citera, Guillermo J. Pons-Estel, Rodrigo García Salinas et autres

El herpes zóster (HZ) representa una complicación relevante en pacientes con enfermedades reumáticas inflamatorias crónicas autoinmunes (ERICA), especialmente en aquellos tratados con glucocorticoides, terapias biológicas e inhibidores de JAK. Este trabajo revisa la evidencia actual sobre el riesgo, impacto clínico y prevención …

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Demographic and clinical characteristics of patients with systemic lupus erythematosus across five registries: the LupusNet federated data network

F. Zazzetti, Ashley Orillion, U. Sbarigia, Anna Sheahan et autres

OBJECTIVE: This study describes baseline demographics, clinical characteristics and treatments of patients diagnosed with systemic lupus erythematosus (SLE) at the time of registration in the registries of the Lupus Federated Data Network (LupusNet). METHODS: Data were collected from five SLE registries in …

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Lupus in Latin America: Where are we now?

Manuel F. Ugarte-Gil, Guillermo J. Pons-Estel, Graciela S. Alarcón

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WCN26-6802 The Impact of Active Lupus Nephritis on Work Productivity in Patients from a Latin American Lupus Cohort

Gustavo Aroca, Romina Nieto, Rosana Quintana, Guillermo J. Pons-Estel et autres

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Global Rheumatology Registries and Cohorts

Manuel F. Ugarte-Gil, Guillermo J. Pons-Estel, Graciela S. Alarcón

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PO:05:138 Measurement of thrombocytopaenia in a novel treatment response measure for systemic lupus erythematosus clinical trials

Kathryn Connelly, Eric F Morand, R. Koelmeyer, Lavanya Rajagopala et autres

Objectives To define a fit-for-purpose clinical outcome assessment for thrombocytopaenia, as part of a novel multi-domain outcome measure for systemic lupus erythematosus (SLE) clinical trials, the Treatment Response Measure for Systemic Lupus Erythematosus (TRM-SLE).Methods An international working group comprising 14 expert clinicians …

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PO:05:140 Measurement of haemolytic anaemia in a novel treatment response measure for systemic lupus erythematosus clinical trials

Kathryn Connelly, Eric F Morand, R. Koelmeyer, Lavanya Rajagopala et autres

Objectives To define a fit-for-purpose clinical outcome assessment, and thresholds for entry and improvement, of haemolytic anaemia, for inclusion as part of a novel multi-domain outcome measure for SLE clinical trials, Treatment Response Measure for Systemic Lupus Erythematosus (TRM-SLE).Methods An international working …

au, es, us, gr, nl, ph, it, gb, ar (code pays fourni par la source)

Protective effect of antimalarials on the most frequently affected damage domains in SLE: Data from a multiethnic Latin American cohort

Rosana Quintana, Guillermo J. Pons-Estel, Daniel Wojdyla, Graciela S. Alarcón et autres

Objective To assess the effect of antimalarials (AMs) on overall damage and on its most frequently affected domains, as measured by the Systemic Lupus International Collaborating Clinics Damage Index (SDI) in patients from the GLADEL cohort. Methods New damage was defined as …

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Measurement of haemolytic anaemia in a novel treatment response measure for SLE clinical trials

Kathryn Connelly, Eric F Morand, R. Koelmeyer, Lavanya Rajagopala et autres

OBJECTIVES: To define a clinically meaningful treatment response definition for haemolytic anaemia, that will form part of a novel multidomain outcome measure for SLE clinical trials. METHODS: An international working group comprising 12 clinicians and 4 patients completed a multistep consensus process. …

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Frequency and associated factors of herpes zoster infection in SLE patients from Latin America: data from the GLADEL 2.0 cohort

Romina Nieto, Lucía Álvarez Hernández, Marina Scolnik, L. Maurelli et autres

OBJECTIVE: The aim of this study was to assess the epidemiological and clinical characteristics of herpes zoster (HZ) and to identify the factors associated with its first episode in Latin American SLE patients. METHODS: GLADEL 2.0 (Grupo Latino Americano De Estudio del …

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Baseline characteristics of patients with SLE with and without lupus nephritis from the Latin American multiethnic GLADEL 2.0 cohort

Guillermo J. Pons-Estel, Romina Nieto, Rosana Quintana, Rosa Serrano Morales et autres

OBJECTIVE: To describe baseline characteristics of a multinational, multiethnic Latin American cohort of SLE patients with and without lupus nephritis (LN) from Latin American Group for the Study of Lupus (GLADEL) 2.0. METHODS: GLADEL 2.0 is an observational prevalent and incident cohort. …

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Epidemiology

Carolina A. Isnardi, Manuel F. Ugarte-Gil, Guillermo J. Pons-Estel, Graciela S. Alarcón

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