RORγt+ APCs require a distinct cis-regulatory element to instruct tolerance to dietary antigens
Jie Zhao, Jiacheng Hao, Jincheng Chen, Mengze Lyu et autres
Oral tolerance represents a hallmark of intestinal mucosal immunity to prevent inflammatory responses to harmless natural antigens, such as dietary components or commensal organisms. According to recent studies, RORγt+ antigen-presenting cell (APC) contributes to intestinal homeostasis, including oral tolerance, through inducing microbiota- …
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1 citation
Nature Communications