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Profil bibliographique

Mengling Chen

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

5Publications signalées
2Citations signalées
4Affiliations récentes

Les institutions déclarées

Les domaines associés

Malaria Research and ControlInsect Resistance and GeneticsInsect-Plant Interactions and ControlPharmacogenetics and Drug MetabolismCannabis and Cannabinoid Research

Les publications récentes

Accès ouvert 2026 article OpenAlex

Virome analysis reveals an arthropod-specific RNA virus that enhances host adaptation to stress

Xin An, Siyu Wei, Mengling Chen, Yufei Shi et autres

Viruses are obligate parasites that rely on host cellular machinery for replication and transmission. Accordingly, arthropod-associated viruses can establish neutral, beneficial, or pathogenic relationships. However, over the past two decades, metatranscriptome studies have uncovered diverse viromes that include many asymptomatic RNA viruses. …

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0 citations Microbiome
Accès ouvert 2026 article OpenAlex

Synergistic action of different molecular mechanisms causes striking levels of insecticide resistance in the malaria vector Anopheles gambiae

Mengling Chen, Latifa Remadi, Dimitra Tsakireli, Emmanouil Kokkas et autres

Intensifying insecticide resistance in the malaria vector Anopheles gambiae poses a serious threat to the progress achieved the last decades in reducing malaria deaths in Africa. The genetic basis of insecticide resistance is often complex, involving multiple genes and mutations. However, we …

gr, bg, gb, us (code pays fourni par la source)

1 citation Proceedings of the National Academy of Sciences
Accès ouvert 2026 preprint OpenAlex

Synergistic action of different molecular mechanisms causes striking levels of insecticide resistance in the malaria vector Anopheles gambiae

Mengling Chen, Latifa Remadi, Dimitra Tsakireli, Emmanouil Kokkas et autres

Abstract Intensifying insecticide resistance in the malaria vector Anopheles gambiae poses a serious threat to the hard-won gains in reducing malaria deaths in Africa. The genetic basis of insecticide resistance is often complex, involving multiple genes and mutations. However, we still lack …

gr, gb (code pays fourni par la source)

1 citation bioRxiv (Cold Spring Harbor Laboratory)
2026 conference-paper OpenAlex

Natural compounds as CYP450 inhibitor scaffolds: Restoring insecticide efficacy through plant-based synergists

Maria Chalkiadaki, Linda Grigoraki, P S Tzimas, Georgia Vasalaki et autres

Mosquito-borne diseases remain a major health challenge [ 1 ]. Vector control relies heavily on synthetic insecticides [ 2 ], which have led to widespread insecticide resistance, largely due to the overexpression of cytochrome P450 monooxygenases (CYPs) [ 3 ]. To identify …

gr (code pays fourni par la source)

0 citations Planta Medica
Accès ouvert 2026 preprint OpenAlex

Mitigating CYP450-Mediated Insecticide Resistance in Malaria Vectors with Cannabis-Derived Synergists: The Potential of Cannabidiol

Maria Chalkiadaki, Linda Grigoraki, Dimitra Tsakireli, Georgia Vasalaki et autres

Abstract Insecticide resistance in mosquitoes, largely mediated by cytochrome P450 monooxygenases (CYPs), compromises the efficacy of vector control tools. In this study, chemically-wise selected natural extracts and compounds were screened for their CYP inhibition potential. Among 37 tested plant extracts and fractions, …

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0 citations bioRxiv (Cold Spring Harbor Laboratory)

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