Cell jamming transition is regulated by mitochondrial pyruvate transport and endocytosis
Alexandra G. Bermudez, Zoe D. Latham, Johnny Diaz, Weihong Yan et autres
Epithelial tissues undergo dynamic transitions between fluid-like collective motion and mechanically jammed states during development, injury repair, and disease progression. However, the cellular programs that drive these transitions and regulate collective behavior remain unclear. Using a controlled crowding model integrated with live-cell …
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bioRxiv (Cold Spring Harbor Laboratory)