Integrated mutational landscape analysis of endometrial stromal sarcoma
Tobias MP Hartwich, Seungji Choi, Ayoung Hwang, Stefania Bellone et autres
Endometrial stromal sarcoma (ESS) is a rare uterine malignancy with limited treatment options. We performed integrated whole-genome, whole-exome, and transcriptome sequencing on 80 ESS tumors, comprising 32 low-grade (LG) and 48 high-grade (HG) tumors, to characterize their genetic landscape. The overall mutation …
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4 citations
Proceedings of the National Academy of Sciences